How many times (mid solo) usually has your pick flown out of those nimble fingers and shot across the stage, once?, twice? three times? Lets be honest, in a live gig once is once too many.
In the past I've tried all the tricks, rubbed a pick with sand paper, got the drummer to stubb out his cigarette on it, tried marking it with my soldering iron, all to no avail.
Now a simple solution, buy these picks. Even with the sweatiest hands I'd defy anyone to drop these picks (ok there'll still be someone who can) but these picks are designed for 99.9% of us guitar players who drop from time to time.
Downside?...only one, if you play an acoustic without the soundhole covered and you drop it inside....well...you're on your own...lol